SKF 38393 hydrochloride
2-phenyl-4-azabicyclo[5.4.0]undeca-7,9,11-triene-9,10-diol
CAS: 62717-42-4
Molecular Formula: C16H17NO2
SKF 38393 hydrochloride - Names and Identifiers
SKF 38393 hydrochloride - Physico-chemical Properties
| Molecular Formula | C16H17NO2 |
| Molar Mass | 291.78 |
| Melting Point | 283-285 °C |
| Solubility | H2O: >5mg/mL |
| Appearance | crystalline |
| Color | white |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| In vitro study | SKF38393 (50-100 μm) induced long-lasting synaptic potentiation in a protein synthesis-dependent manner. In rat prefrontal cortex neurons in vitro, SKF 38393 mimic the effects of DA on I(NaP) and modulate persistent sodium currents. In the auditory cortex, SKF38393 affects long-term memory formation and consolidation by activating downstream effector adenylate cyclase and phospholipase C- significant proteomic alterations. |
| In vivo study | SKF38393(6 mg/kg, I. p.) prevented scopolamine-induced memory impairment in the T-maze test. In adult male NMRI mice, SKF38393 (1 μg/mouse) impairs fear learning. |
SKF 38393 hydrochloride - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
SKF 38393 hydrochloride - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.427 ml | 17.136 ml | 34.272 ml |
| 5 mM | 0.685 ml | 3.427 ml | 6.854 ml |
| 10 mM | 0.343 ml | 1.714 ml | 3.427 ml |
| 5 mM | 0.069 ml | 0.343 ml | 0.685 ml |
Last Update：2024-01-02 23:10:35
SKF 38393 hydrochloride - Reference Information
| biological activity | SKF38393 HCl is a selective dopamine D1/D5 receptor agonist. |
| Target | Value |
Last Update：2024-04-09 20:49:11
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Spot supply
Product Name: 2-phenyl-4-azabicyclo[5.4.0]undeca-7,9,11-triene-9,10-diol Visit Supplier Webpage Request for quotationCAS: 62717-42-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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